https://ashin2117.r-universe.devRecent package updates in ashin2117R-universehttps://github.com/ashin2117.pnghttps://ashin2117.r-universe.devWed, 07 Oct 2026 08:10:20 GMTashin2@uw.edu (Andrew Shin)Provides tools to model overdispersed vaccine-specific memory B cell frequencies using Beta-Binomial generalized linear models, specifically designed for analyzing vaccine-induced cellular immune responses. Includes method-of-moments dispersion estimation, likelihood ratio testing across experimental arms, and Monte Carlo simulation frameworks to calculate statistical power and Type I error rates. The methodologies are directly motivated by the analysis of immunology data in 'Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial' (Parks et al. 2025) <doi:10.1126/scitranslmed.ady6831>.https://github.com/r-universe/ashin2117/actions/runs/37771823271Wed, 07 Oct 2026 08:10:20 GMTBBMBC0.1.0successhttps://ashin2117.r-universe.devhttps://github.com/cran/BBMBC